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KMID : 0616119830140010030
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Korean Journal of Pharmacognosy
1983 Volume.14 No. 1 p.30 ~ p.38
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Studies on the Efficacy of Combined Preparation of Crude Drugs ( ⅩⅢ ) Effects of “ Daeshiho - Tang ”on the Blood Vessels , Activities of the Liver Enzyme , biliary Secretory and Anti - diabetic Actions
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홍남두/Hong ND
장인규/김남재/손정곤/Chang IK/Kim NJ/Shon JG
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Abstract
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These studies were conducted in an attempt to investigate effects of "Daeshiho-Tang" on the blood vessels, activities of liver enzyme and excretory action of bile juice in serum of CCl₄-intoxicated rabbits, glucose and total cholesterol levels in serum of alloxan-induced diabetic rabbits. The result of these studies were summerized as follows; 1. Hypotensive and vaso-dilatating actions due to vascular smooth muscle relaxation were noted in frogs, rabbits and dogs. 2. GOT, GPT and total cholesterol in serum of CCl₄-intoxicated rabbits showed significant depressive effects. 3. Significantly increased biliary secretory effect was noted in CCl₄-intoxicated rabbits. 4. Glucose and total cholesterol levels showed markedly decraese in alloxan-induced diabetic rabbits. Considering the experimental studies results, it is suggested that "Daeshiho-Tang" has therapeutic efficacy to treat febrile diseses and metabolic diseases.
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